Research

We conduct methodological research in functional genomics technologies, bioinformatics and data integration. On the experimental technology side as well as on the informatics side. We develop, implement and validate new methods that advance the accuracy and usability of functional technologies.

Research projects are either conducted as FGCZ internal projects or in collaboration with an FGCZ user group.

The current and recent projects are:

• protViz: An R-package for Proteomics Data Analysis & Visualization
• B-Fabric: a framework for data management and information integration
• BattleX: Manipulating the fight between human host cells and intracellular pathogens

Past method and tool development projects were:

• Top3ProteinQuantitation T3PQ: Protein quantitation using the best flying peptides
• DeltaTectra: Computational approach to detect PTMs
• MAGMA: a web application for the quick but nevertheless powerful statistical analysis of two-channel data
• MAP: using association rules to detect gene sets that are coregulated throughout subsets of conditions
• Analysis-Driven Experimentation: statistical data analysis to improve the proteome coverage of shotgun proteomics
• Peptoscope: prototype application to specifically detect PTMs
• Phylochip: statistical strain identification with diagnostic microarrays
• Surface Chemistry: optimized coatings for microarray glass slides

Newly developed methods are applied in User Lab research projects and larger collaborative networks including

• BattleX / SystemsX.ch
• PRIME-XS

Research and Development is supported by:

In collaboration with

Contact

Ralph Schlapbach